Tramazoline is a chemical that is used in the form of tramazoline hydrochloride in nasal decongestant preparations.[1] It is an α-adrenergic receptor agonist that inhibits secretion of nasal mucus.

Tramazoline
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.012.823 Edit this at Wikidata
Chemical and physical data
FormulaC13H17N3
Molar mass215.300 g·mol−1
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It was patented in 1961 and came into medical use in 1962.[2]

Brand names

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  • Australia
    • Spray-Tish[3]
    • Rhinaspray
  • Austria
    • Rhinorix
  • Belgium
    • Rhinospray
  • Bulgaria
    • Muconasal Plus
  • Czech Republic
    • Muconasal Plus
  • Germany
    • Biciron
    • Ellatun
    • Rhinospray
  • Hungary
    • Rhinospray Plus
  • Italy
    • Rinogutt
    • Fexallegra nasale (Tramazoline + Chlorpheniramine, 1 mg/mL + 3.55 mg/mL)
  • The Netherlands
    • Bisolnasal
  • Portugal
    • Rhinospray
  • Romania
    • Muconasal Plus (older)
    • Muconasal (newer)
  • Russia
  • Spain
    • Rhinospray
  • Slovakia
    • Muconasal Plus
  • Ukraine
    • Lasorin

References

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  1. ^ "Spray-Tish Consumer Information". MyDr.com.au. Retrieved 16 April 2011.
  2. ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 552. ISBN 978-3-527-60749-5.
  3. ^ "Consumer medicine information: Spray-Tish". nps.org.au. NPS MedicineWise. 8 September 2017. Retrieved September 13, 2021.