TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose-forming)

TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose-forming) (EC 5.3.2.4, TDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase, Tyl1a, dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase) is an enzyme with systematic name dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose:dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose isomerase.[1] This enzyme catalyses the following chemical reaction

TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose-forming)
Identifiers
EC no.5.3.2.4
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dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose

The enzyme is involved in biosynthesis of D-mycaminose.

References

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  1. ^ Melançon CE, Hong L, White JA, Liu YN, Liu HW (January 2007). "Characterization of TDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from the D-mycaminose biosynthetic pathway of Streptomyces fradiae: in vitro activity and substrate specificity studies". Biochemistry. 46 (2): 577–90. doi:10.1021/bi061907y. PMC 2515277. PMID 17209568.
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