Suman Kumar Dhar (born 1968) is an Indian molecular biologist and a professor at the Special Centre for Molecular Medicine of Jawaharlal Nehru University.[1] He is known for his studies on the DNA replication and cell cycle regulation in Helicobacter pylori and Plasmodium falciparum, two pathogens affecting humans.[2] An elected fellow of the National Academy of Sciences, India, Indian National Science Academy[3] and the Indian Academy of Sciences,[4] he is also a recipient of the National Bioscience Award for Career Development of the Department of Biotechnology in 2010.[5] The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2012, for his contributions to biological sciences.[6]

Suman Kumar Dhar
Born (1968-03-06) 6 March 1968 (age 56)
NationalityIndian
Alma mater
Known forStudies on Helicobacter pylori and Plasmodium falciparum
Awards
Scientific career
Fields
Institutions

Biography

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Suman Kumar Dhar, born on 6 March 1968 in the Indian state of West Bengal, graduated in chemistry from Burdwan University in 1989 and completed his master's degree in biochemistry in 1992 from Kalyani University before securing a PhD in molecular biology from Jawaharlal Nehru University (JNU) in 1998.[7]

He worked from 1997 to 1998 as a research assistant at the department of microbiology of the University of Nebraska. Next, he did his post-doctoral studies at Brigham and Women’s Hospital of Harvard Medical School which he completed in 2001.[8]

Returning to India the same year, he joined Jawaharlal Nehru University as an assistant professor at the Special Centre for Molecular Medicine (SCMM) of the university where he rose in ranks to become an associate professor in 2005 and a professor in 2011, finally reaching the position of the chairperson of SCMM in 2011. In

between, he served as a visiting fellow at Harvard Medical School from 2002 to 2003), the Harvard School of Public Health from 2003 and 2004, and the Bernhard Nocht Institute for Tropical Medicine in 2007. He also served as a Humboldt Research Fellow at Bernhard Nocht Institute in 2008. Besides his academic duties at JNU, Dhar is involved in the establishment of Centre of Excellence in Parasitology, a Department of Biotechnology-funded project.[7] He was also a member of the proctorial committee constituted by JNU to inquire about the 2016 JNU protests.[9][10]

Career

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Dhar's research history starts during his graduate studies when he worked on Entamoeba histolytica, the protozoan which causes amoebiasis, focusing on its ribosomal DNA circle.[11] Later at Harvard Medical School, his post-doctoral studies were centered on mammalian DNA replication which assisted him to identify the ORC6 (origin recognition complex subunit six) and its role in viral DNA replication. He also identified geminin, a replication inhibitor, as a blocking factor of viral DNA replication, a discovery which earned him a US patent.[7] Later, he studied the human pathogens, Helicobacter pylori and Plasmodium falciparum and their DNA replication and cell cycle regulation.[12] He also worked on anti-malarial drugs and proposed Acriflavine as an anti-malarial agent, which has also been patented by him.[13] His work has identified PfGyrase for P. falciparum and HpDnaB helicase for H. pylori as targets[14] and these researches are reported to be helpful in drug discovery efforts for Gastric ulcers, Gastric adenocarcinomas and Malaria.[15] Dhar has documented his research by way of a number of articles[note 1] and online repositories such as PubMed[16] and Pubfacts have listed many of them.[17] He has contributed chapters to three books which include Epigenetics: Development and Disease by Tapas Kumar Kundu.[18] He is associated with many science journals such as Journal of Biological Chemistry, Molecular Microbiology, FEBS Journal and Medical Science Monitor as an ad-hoc reviewer and has delivered featured talks including his oration at the Gordon Research Conference on Host-Parasite interaction held in Rhode Island in 2012.[7]

Awards and honors

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While in the US, Dhar received two grants for his researches, a grant from the National Institutes of Health for studies on emerging infectious diseases (1997–98) and the United States Department of the Army grant for research on breast cancer (2000–03).[7] He received the Senior International Research Fellowship of the Wellcome Trust in 2005, the tenancy of the fellowship extending to 2010, and on its expiry, he received the Wellcome Trust-DBT Senior Research Fellowship in 2010. In 2006, Dhar received the Swarnajayanthi Fellowship of the Department of Biotechnology (DBT)[19] and four years later, DBT honored him again with the 2010 National Bioscience Award for Career Development.[5] He was elected to the Guha Research Conference in 2007 and the next year brought him the Alexander Von Humboldt Fellowship and the Swarnajayanti Fellowship of the Department of Science and Technology.[20]

A member of the American Society for Microbiology, Dhar was awarded the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, by the Council of Scientific and Industrial Research in 2012.[6] The National Academy of Sciences, India elected him as a fellow in 2011[21] and he became a fellow of the Indian National Science Academy and the Indian Academy of Sciences in 2016.[3][4]

Patents

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  • Anindya Dutta, Suman Kumar Dhar (2001). "Geminin and ORC3N Inhibit Replication of Herpes Viruses, Pamiloma Viruses and Polyoma Viruses" (PDF). Patent No. No. B0801.70253US00. Dhar Suman Kumar.
  • Suman Kumar Dhar; Srikanta Dana; Dhaneswar Prusty; Ashraf Dar; Pritam Mukhopadhyay (24 August 2012). "Method of screening anti-plasmodial activity of acriflavin and acriflavin as an anti-malarial agent". Patent No. WO2014030171 A1. Dhar Suman Kumar.

Selected bibliography

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See also

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Notes

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  1. ^ Please see Selected bibliography section

References

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  1. ^ "Winners of Shanti Swarup Bhatnagar Awards 2012". Indian Academy of Sciences. 28 September 2012. Retrieved 2 November 2016.
  2. ^ "Brief Profile of the Awardee". Shanti Swarup Bhatnagar Prize. 2016. Retrieved 5 October 2016.
  3. ^ a b "Indian fellow". Indian National Science Academy. 2016. Retrieved 2 November 2016.
  4. ^ a b "Fellow Profile". Indian Academy of Sciences. 2016. Retrieved 2 November 2016.
  5. ^ a b "Awardees of National Bioscience Awards for Career Development" (PDF). Department of Biotechnology. 2016. Retrieved 17 October 2016.
  6. ^ a b "View Bhatnagar Awardees". Shanti Swarup Bhatnagar Prize. 2016. Retrieved 12 November 2016.
  7. ^ a b c d e "Faculty profile" (PDF). Jawaharlal Nehru University. 2016. Retrieved 2 November 2016.
  8. ^ "Decoding deadly pathogens - Dr Suman Kumar Dhar". Biospectrum India. 12 December 2012. Retrieved 2 November 2016.
  9. ^ "Afzal Guru protests: Police slap charges of sedition, conspiracy". Indian Express. 12 February 2016. Retrieved 2 November 2016.
  10. ^ "Arrest 'Anti India Elements' Says Rajnath, So Police Pin 'Sedition' on JNUSU Head". The Wire. 13 February 2016. Retrieved 2 November 2016.
  11. ^ "Suman Kumar Dhar, Associate Professor and present Chairperson". JNU - SCMM. 2016. Retrieved 2 November 2016.
  12. ^ "Handbook of Shanti Swarup Bhatnagar Prize Winners" (PDF). Council of Scientific and Industrial Research. 1999. p. 34. Retrieved 5 October 2016.
  13. ^ "US Patent Issued to Suman Kumar Dhar on June 28 for "Method of Screening Anti-Plasmodial Activity of Acriflavin and Acriflavin as an Anti-Malarial Agent"". 28 June 2016. Archived from the original on 11 September 2018. Retrieved 2 November 2016.
  14. ^ "Suman Kumar Dhar on Global Professor Rank". Global Professor Rank. 2016. Retrieved 2 November 2016.
  15. ^ Ajeena Ramanujan (2 October 2012). "Shanti Swarup Bhatnagar Award in Biological Sciences - Suman Dhar". India Bioscience.
  16. ^ "Dhar on PubMed". PubMed. 2016. Retrieved 2 November 2016.
  17. ^ "Dhar on Pubfacts". Pubfacts. 2016. Retrieved 2 November 2016.
  18. ^ Tapas Kumar Kundu (2012). Epigenetics: Development and Disease. Springer Science & Business Media. pp. 659–. ISBN 978-94-007-4525-4.
  19. ^ "Swarnajayanthi Fellowship" (PDF). Department of Biotechnology. 2006. Retrieved 1 November 2016.
  20. ^ "SwarnaJayanti Fellowship Awards" (PDF). Department of Science and Technology. 2007. Retrieved 3 November 2016.
  21. ^ "NASI fellows". National Academy of Sciences, India. 2016. Retrieved 2 November 2016.
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