Sulfamethoxypyridazine

Sulfamethoxypyridazine is a sulfonamide antibacterial.[1]

Sulfamethoxypyridazine
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.001.157 Edit this at Wikidata
Chemical and physical data
FormulaC11H12N4O3S
Molar mass280.30 g·mol−1
3D model (JSmol)
  • O=S(=O)(Nc1nnc(OC)cc1)c2ccc(N)cc2
  • InChI=1S/C11H12N4O3S/c1-18-11-7-6-10(13-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15) checkY
  • Key:VLYWMPOKSSWJAL-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

It is prescribed for vaginal irritation, and severe acute thrush.

It is also used in the treatment of Dermatitis herpetiformis,[2] where it is an alternative therapy to Dapsone.

Sulfamethoxypyridazine is supplied as 500mg tablets.

References

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  1. ^ Boger WP, Gylfe JM, Strickland CS (November 1956). "Sulfamethoxypyridazine (Kynex), a new long-acting sulfonamide". Antibiotic Medicine & Clinical Therapy. 3 (6). New York, NY: 378–87. PMID 13363378.
  2. ^ Vilanova X, De Moragas JM (October 1959). "[Treatment of dermatitis herpetiformis (Duhring) and herpes gestationis with sulfamethoxypyridazine]". Actas Dermo-sifiliograficas (in Spanish). 50: 439–42. PMID 13842251.