Splicing factor, suppressor of white-apricot homolog is a protein in humans that is encoded by the SFSWAP gene.[5]

SFSWAP
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSFSWAP, SFRS8, SWAP, splicing factor SWAP homolog, splicing factor SWAP
External IDsOMIM: 601945; MGI: 101760; HomoloGene: 134548; GeneCards: SFSWAP; OMA:SFSWAP - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001261411
NM_004592
NM_152235

RefSeq (protein)

NP_001248340
NP_004583

NP_758480
NP_001346881
NP_001365844
NP_001365845
NP_001365846

Location (UCSC)Chr 12: 131.71 – 131.8 MbChr 5: 129.58 – 129.65 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a human homolog of Drosophila splicing regulatory protein. This gene autoregulates its expression by control of splicing of its first two introns. In addition, it also regulates the splicing of fibronectin and CD45 genes. Two transcript variants encoding different isoforms have been identified.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000061936Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029439Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: Splicing factor, suppressor of white-apricot homolog (Drosophila)". Retrieved 2013-05-08.
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  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Splicing factor, suppressor of white-apricot homolog (SFSWAP)