Splicing factor, arginine/serine-rich 6 is a protein that in humans is encoded by the SFRS6 gene.[5][6]

SRSF6
Identifiers
AliasesSRSF6, B52, HEL-S-91, SFRS6, SRP55, serine/arginine-rich splicing factor 6, serine and arginine rich splicing factor 6
External IDsOMIM: 601944; MGI: 1915246; HomoloGene: 110783; GeneCards: SRSF6; OMA:SRSF6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006275

NM_026499

RefSeq (protein)

NP_006266

NP_080775

Location (UCSC)Chr 20: 43.46 – 43.47 MbChr 2: 162.77 – 162.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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The protein encoded by this gene is involved in mRNA splicing and may play a role in site selection in alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000124193Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000016921Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Screaton GR, Cáceres JF, Mayeda A, Bell MV, Plebanski M, Jackson DG, Bell JI, Krainer AR (September 1995). "Identification and characterization of three members of the human SR family of pre-mRNA splicing factors". The EMBO Journal. 14 (17): 4336–49. doi:10.1002/j.1460-2075.1995.tb00108.x. PMC 394518. PMID 7556075.
  6. ^ a b "Entrez Gene: SFRS6 splicing factor, arginine/serine-rich 6".

Further reading

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