Quercetin-3,3'-bissulfate 7-sulfotransferase

In enzymology, a quercetin-3,3'-bissulfate 7-sulfotransferase (EC 2.8.2.28) is an enzyme that catalyzes the chemical reaction

quercetin-3,3'-bissulfate 7-sulfotransferase
Identifiers
EC no.2.8.2.28
CAS no.121855-13-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins
3'-phosphoadenylyl sulfate + quercetin 3,3'-bissulfate adenosine 3',5'-bisphosphate + quercetin 3,7,3'-trisulfate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and quercetin 3,3'-bissulfate, whereas its two products are adenosine 3',5'-bisphosphate and quercetin 3,7,3'-trissulfate.

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:quercetin-3,3'-bissulfate 7-sulfotransferase. Other names in common use include flavonol 7-sulfotransferase, 7-sulfotransferase, and PAPS:flavonol 3,3'/3,4'-disulfate 7-sulfotransferase.

References

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  • Varin L (1988). "Enzymatic synthesis of sulfated flavonoids in Flaveria spp". Bull. Liaison-Groupe Polyphenols. 14: 248–257.