An oncocyte is an epithelial cell characterized by an excessive number of mitochondria, resulting in an abundant acidophilic, granular cytoplasm. Oncocytes can be benign or malignant.

Cytopathology of Warthin's tumor, with typical cellular features (and a relatively uncommon binucleated cell).[1] Pap stain. The relatively large size of the oncocytes is seen when comparing to the lymphocyte.
Micrograph showing apocrine-type metaplasia of the breast with typical oncocytes.[2] H&E stain.
Oncocytes (left of image), as seen in a renal oncocytoma. H&E stain.

Other names

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Also known as:

Etymology

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Derived from the Greek root onco-, which means mass, bulk.

See also

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References

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  1. ^ Image by Mikael Häggström, MD. References for entries:
    - Köybaşioğlu FF, Önal B, Han Ü, Adabağ A, Şahpaz A (2020). "Cytomorphological findings in diagnosis of Warthin tumor". Turk J Med Sci. 50 (1): 148–154. doi:10.3906/sag-1901-215. PMC 7080357. PMID 31769640.{{cite journal}}: CS1 maint: multiple names: authors list (link)
    Binucleation:
    - Dr.S. Malliga (2006-10-18). "A correlative cytological and histopathological study on lesions of salivary gland" (PDF).
    - Chan MKM, McGuire LJ: Cytodiagnosis of Lesions Presenting as Salivary Gland Swellings: A Report of Seven Cases. Diagn Cytopathol 8: 439-443, 1992b.
  2. ^ Image by Mikael Häggström, MD. Reference for findings: Carlos C. Diez Freire, M.D., Shahla Masood, M.D. "Apocrine metaplasia". Pathology Outlines.{{cite web}}: CS1 maint: multiple names: authors list (link) Last author update: 28 May 2020.
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