N,N-Diisopropylaminoethanol

N,N-Diisopropylaminoethanol (DIPA) is a processor for production of various chemicals and also an intermediate in the production of the nerve agents VX and NX. [2] It is a colorless liquid, although aged samples can appear yellow.

N,N-Diisopropylaminoethanol
Skeletal formula of N,N-diisopropylaminoethanol with some implicit hydrogens shown
Names
Preferred IUPAC name
2-[Di(propan-2-yl)amino]ethan-1-ol
Other names
2-[Di(propan-2-yl)amino]ethanol
2-(Diisopropylamino)ethanol
Identifiers
3D model (JSmol)
1697955
ChEMBL
ChemSpider
ECHA InfoCard 100.002.307 Edit this at Wikidata
EC Number
  • 202-536-2
MeSH 2-diisopropylaminoethanol
RTECS number
  • KK5950000
UNII
UN number 2922
  • InChI=1S/C8H19NO/c1-7(2)9(5-6-10)8(3)4/h7-8,10H,5-6H2,1-4H3 checkY
    Key: ZYWUVGFIXPNBDL-UHFFFAOYSA-N checkY
  • CC(C)N(CCO)C(C)C
Properties
C8H19NO
Molar mass 145.246 g·mol−1
Appearance Colorless liquid
Odor Ammoniacal
Density 826 mg mL−1
Melting point −39.2 °C; −38.6 °F; 233.9 K
Boiling point 190.1 °C; 374.1 °F; 463.2 K
log P 1.476
Vapor pressure <100 Pa (at 20 °C)
1.442
Hazards
GHS labelling:
GHS05: Corrosive GHS06: Toxic
H302, H311, H314, H331
P261, P280, P305+P351+P338, P310
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 2: Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury. E.g. chloroformFlammability 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g. canola oilInstability 1: Normally stable, but can become unstable at elevated temperatures and pressures. E.g. calciumSpecial hazards (white): no code
2
1
1
Flash point 64 °C (147 °F; 337 K)
Lethal dose or concentration (LD, LC):
  • 394 mg kg−1 (dermal, rabbit)
  • 860 mg kg−1 (oral, rat)
Safety data sheet (SDS) [1]
Related compounds
Related alkanols
Related compounds
Diethylhydroxylamine
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Health effects

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Inhalation and skin contact are expected to be the primary ways of occupational exposure to this chemical. Based on single exposure animal tests, it is considered to be slightly toxic if swallowed or inhaled, moderately toxic if absorbed through skin as well as being corrosive to eyes and skin.[1] Vapor may be irritating to the eyes and upper respiratory tract. Temporary and reversible visual disturbances characterized by mildly blurred vision, a blue-gray discolorization of sight (blue haze) or halo vision (appearance of a halo when looking at light sources) may also occur.[citation needed]

References

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  1. ^ a b "SAFETY DATA SHEET 2--(Diisopropylamino)ethanol". SigmaAldrich. MilliporeSigma. November 14, 2021. Retrieved April 27, 2022.
  2. ^ Suzuki, Osamu; Kanako Watanabe, eds. (2005). Drugs and poisons in humans : a handbook of practical analysis (1. Aufl. ed.). Berlin [u.a.]: Springer. pp. 69–90. doi:10.1007/3-540-27579-7_9. ISBN 978-3-540-22277-4.