Mannosylglycerate synthase

Mannosylglycerate synthase (EC 2.4.1.269) is an enzyme with systematic name GDP-mannose:D-glycerate 2-alpha-D-mannosyltransferase.[1][2] This enzyme catalyses the following chemical reaction

Mannosylglycerate synthase
Identifiers
EC no.2.4.1.269
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins
GDP-mannose + D-glycerate GDP + 2-O-(alpha-D-mannopyranosyl)-D-glycerate

Depending on conditions mannosylglycerate synthase is more or less specific for the GDP-mannose and D-glycerate.

See also

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References

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  1. ^ Martins LO, Empadinhas N, Marugg JD, Miguel C, Ferreira C, da Costa MS, Santos H (December 1999). "Biosynthesis of mannosylglycerate in the thermophilic bacterium Rhodothermus marinus. Biochemical and genetic characterization of a mannosylglycerate synthase". The Journal of Biological Chemistry. 274 (50): 35407–14. doi:10.1074/jbc.274.50.35407. PMID 10585410.
  2. ^ Flint J, Taylor E, Yang M, Bolam DN, Tailford LE, Martinez-Fleites C, Dodson EJ, Davis BG, Gilbert HJ, Davies GJ (July 2005). "Structural dissection and high-throughput screening of mannosylglycerate synthase". Nature Structural & Molecular Biology. 12 (7): 608–14. doi:10.1038/nsmb950. PMID 15951819.
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