Growth differentiation factor 1 (GDF1) is a protein that in humans is encoded by the GDF1 gene.[5]

GDF1
Identifiers
AliasesGDF1, DORV, DTGA3, RAI, growth differentiation factor 1, CHTD6, UOG1, LASS1, CERS1, LAG1
External IDsOMIM: 602880; MGI: 95683; HomoloGene: 105644; GeneCards: GDF1; OMA:GDF1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001492
NM_001387438

NM_001163282
NM_008107

RefSeq (protein)

NP_001483

NP_001156754
NP_032133

Location (UCSC)Chr 19: 18.87 – 18.9 MbChr 8: 70.78 – 70.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

GDF1 belongs to the transforming growth factor beta superfamily that has a role in left-right patterning and mesoderm induction during embryonic development.[6] It is found in the brain, spinal cord and peripheral nerves of embryos.[5][6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000130283Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000109523Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Lee SJ (May 1991). "Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure". Proc. Natl. Acad. Sci. U.S.A. 88 (10): 4250–4. Bibcode:1991PNAS...88.4250L. doi:10.1073/pnas.88.10.4250. PMC 51636. PMID 2034669.
  6. ^ a b Rankin CT, Bunton T, Lawler AM, Lee SJ (March 2000). "Regulation of left-right patterning in mice by growth/differentiation factor-1". Nat. Genet. 24 (3): 262–5. doi:10.1038/73472. PMID 10700179. S2CID 6787053.

Further reading

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