In enzymology, a flavanone 4-reductase (EC 1.1.1.234) is an enzyme that catalyzes the chemical reaction

flavanone 4-reductase
Identifiers
EC no.1.1.1.234
CAS no.115232-53-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins
(2S)-flavan-4-ol + NADP+ (2S)-flavanone + NADPH + H+

Thus, the two substrates of this enzyme are (2S)-flavan-4-ol and NADP+, whereas its 3 products are (2S)-flavanone, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (2S)-flavan-4-ol:NADP+ 4-oxidoreductase. This enzyme participates in flavonoid biosynthesis.

References

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  • Stich K, Forkmann G (1988). "Biosynthesis of 3-deoxyanthocyanins with flower extracts from Sinningia cardinalis". Phytochemistry. 27 (3): 785–789. doi:10.1016/0031-9422(88)84093-7.