Dixin is a protein that in humans is encoded by the DIXDC1 gene.[5][6] When active it stops cancer metastasis due to extreme stickiness, both in vitro and in vivo.[7]

DIXDC1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesDIXDC1, CCD1, DIX domain containing 1
External IDsOMIM: 610493; MGI: 2679721; HomoloGene: 82369; GeneCards: DIXDC1; OMA:DIXDC1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001037954
NM_001278542
NM_033425

NM_178118
NM_001311069
NM_001374656

RefSeq (protein)

NP_001033043
NP_001265471
NP_219493

NP_001297998
NP_835219
NP_001361585

Location (UCSC)Chr 11: 111.93 – 112.02 MbChr 9: 50.57 – 50.65 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000150764Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032064Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Katoh M, Katoh M (July 2003). "KIAA1735 gene on human chromosome 11q23.1 encodes a novel protein with myosine-tail homologous domain and C-terminal DIX domain". International Journal of Oncology. 23 (1): 145–50. doi:10.3892/ijo.23.1.145. PMID 12792787.
  6. ^ "Entrez Gene: DIXDC1 DIX domain containing 1".
  7. ^ "New gene discovered that stops the spread of deadly cancer".

Further reading

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