D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase

D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase (EC 2.7.7.71, hddC (gene), gmhD (gene)) is an enzyme with systematic name GTP:D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase.[1] This enzyme catalyses the following chemical reaction

D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase
Identifiers
EC no.2.7.7.71
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins
D-glycero-alpha-D-manno-heptose 1-phosphate + GTP GDP-D-glycero-alpha-D-manno-heptose + diphosphate

The enzyme is involved in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose.

References

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  1. ^ Kneidinger B, Graninger M, Puchberger M, Kosma P, Messner P (June 2001). "Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose". The Journal of Biological Chemistry. 276 (24): 20935–44. doi:10.1074/jbc.m100378200. PMID 11279237.
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