Cytosol alanyl aminopeptidase

Cytosol alanyl aminopeptidase (EC 3.4.11.14, arylamidase, aminopolypeptidase, thiol-activated aminopeptidase, human liver aminopeptidase, puromycin-sensitive aminopeptidase, soluble alanyl aminopeptidase, cytosol aminopeptidase III, alanine aminopeptidase) is an enzyme.[1][2][3]

Cytosol alanyl aminopeptidase
Identifiers
EC no.3.4.11.14
CAS no.243859-94-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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NCBIproteins

This enzyme catalyses the release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides.

This puromycin-sensitive enzyme is a Co2+-activated zinc-sialoglycoprotein.

References

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  1. ^ Starnes WL, Behal FJ (July 1974). "A human liver aminopeptidase. The amino acid and carbohydrate content, and some physical properties of a sialic acid containing glycoprotein". Biochemistry. 13 (16): 3221–7. doi:10.1021/bi00713a004. PMID 4841062.
  2. ^ Kao YJ, Starnes WL, Behal FJ (July 1978). "Human kidney alanine aminopeptidase: physical and kinetic properties of a sialic acid containing glycoprotein". Biochemistry. 17 (15): 2990–4. doi:10.1021/bi00608a008. PMID 698181.
  3. ^ Sidorowicz W, Hsia WC, Maslej-Zownir O, Behal FJ (November 1980). "Multiple molecular forms of human alanine aminopeptidase: immunochemical properties". Clinica Chimica Acta; International Journal of Clinical Chemistry. 107 (3): 245–56. doi:10.1016/0009-8981(80)90452-0. PMID 6108169.
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