Alpha,alpha-trehalose phosphorylase

In enzymology, an alpha,alpha-trehalose phosphorylase (EC 2.4.1.64) is an enzyme that catalyzes the chemical reaction

alpha,alpha-trehalose phosphorylase
Identifiers
EC no.2.4.1.64
CAS no.37205-59-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins
alpha,alpha-trehalose + phosphate D-glucose + beta-D-glucose 1-phosphate

Thus, the two substrates of this enzyme are trehalose and phosphate, whereas its two products are D-glucose and beta-D-glucose 1-phosphate.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is alpha,alpha-trehalose:phosphate beta-D-glucosyltransferase. This enzyme is also called trehalose phosphorylase. This enzyme participates in starch and sucrose metabolism.

References

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  • Belocopitow E, Marechal LR (1970). "Trehalose phosphorylase from Euglena gracilis". Biochim. Biophys. Acta. 198 (1): 151–4. doi:10.1016/0005-2744(70)90045-8. PMID 5413942.