Asoxime chloride

(Redirected from HI-6)

Asoxime chloride, or more commonly HI-6, is a Hagedorn oxime used in the treatment of organophosphate poisoning.[1]

Asoxime chloride
Clinical data
Routes of
administration
Intramuscular injection
ATC code
  • none
Legal status
Legal status
  • Experimental
Identifiers
  • 4-carbamoyl-1-[({2-[(E)-(hydroxyimino)methyl]pyridinium-1-yl}methoxy)methyl]pyridinium dichloride
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H16Cl2N4O3
Molar mass359.21 g·mol−1
3D model (JSmol)
  • C1=CC=[N+](C(=C1)/C=N/O)COC[N+]2=CC=C(C=C2)C(=O)N.[Cl-].[Cl-]
  • InChI=1S/C14H14N4O3.2ClH/c15-14(19)12-4-7-17(8-5-12)10-21-11-18-6-2-1-3-13(18)9-16-20;;/h1-9H,10-11H2,(H-,15,19);2*1H checkY
  • Key:QELSIJXWEROXOE-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

See also

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References

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  1. ^ Cochran R, Kalisiak J, Küçükkilinç T, Radic Z, Garcia E, Zhang L, et al. (August 2011). "Oxime-assisted acetylcholinesterase catalytic scavengers of organophosphates that resist aging". The Journal of Biological Chemistry. 286 (34): 29718–24. doi:10.1074/jbc.M111.264739. PMC 3191013. PMID 21730071.