T-cell surface glycoprotein CD3 gamma chain is a protein that in humans is encoded by the CD3G gene.

CD3G
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCD3G, CD3-GAMMA, IMD17, T3G, CD3g molecule, CD3GAMMA, CD3 gamma subunit of T-cell receptor complex
External IDsOMIM: 186740; MGI: 88333; HomoloGene: 55; GeneCards: CD3G; OMA:CD3G - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000073

NM_009850

RefSeq (protein)

NP_000064

NP_033980

Location (UCSC)Chr 11: 118.34 – 118.36 MbChr 9: 44.88 – 44.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

T cell antigen receptor (TCR) is associated on the T cell surface with a complex of protein called CD3. CD3G (gamma chain) is one of the four peptides (gamma, delta, epsilon and zeta) that form CD3. Defects in CD3G are associated with T cell immunodeficiency.[5]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000160654Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000002033Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: CD3G CD3g molecule, gamma (CD3-TCR complex)".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.